However, it could also be the reaction if your company is approaching or is currently in a busy season and needs the additional staff, or it's experiencing unusual circumstances, like a hiring freeze, which would prevent it from replacing you entirely.
Spot the Signs. Do you have a good relationship with your manager? Is he or she relatively reasonable? Do you have regular one_on_ones where you talk about your career goals and growth? If so, it's likely that your boss will accept your resignation with grace, help develop a plan of action for your last two weeks, and maybe even attend your farewell happy hour.