Prepare for It. Your best option in this scenario is to accept it with dignity and make sure you're ready to leave the office for good when you turn in your resignation letter, whether that means gathering up your personal items or making sure you've collected the names and contact information for the teammates and clients you'd like to stay in touch with.
These are vague... are you available to train a replacement anytime, even after your last day? Are you saying you'll be too busy to help prepare someone else or that you'll be busy helping with the transition? As with everything else in your resignation letter, clear and concise are the way to go.