Sure, it may sit in the depths of HR until the end of time, but you can be sure of two things: One, your former boss (and future reference) will read it and be impressed. And two, if you ever decide to come back to your company (hey, it happens), it's a very good thing that last thing on file is a great, professionally written resignation letter.
State Your Intent. The whole theme of your resignation letter is the statement that, well, you resign. You don't need to play coy__the time has passed for you to fish around for a counteroffer if it's gotten this far. At this point, you've made your decision to leave, and this letter needs to reflect that.