Why a Resignation Letter? In these digital times, why should we submit a resignation letter, anyway? A paper trail does seem old_fashioned, but in this case, it's a best practice. It makes your intentions clear, as well as the conditions. You're removing any ambiguity about the end of your time there.
Prepare for It. This one is easy. All you have to do is smile and say "Thank you so much for your support. I've enjoyed my time here and I've learned a lot from you. Let me know what I can do to make the transition easier." Are you always going to get reaction number five? Probably not. But if you look for the signs, you can likely anticipate your boss' response, go into the conversation prepared, and come out stronger on the other side. Then, you can breathe a sign of relief and start looking forward to starting your new position.