Also think about your relationship with your manager. Would he or she have reason to think that you'll waste your last two weeks or distract your co_workers instead of doing what you can to make the transition seamless? If so, you may be asked to cut your two weeks short.
You'll have plenty of time to vent personally about your work grievances as you leave, but really, you stand to gain nothing by putting negativity into your resignation letter. And unless you're leaving the state and your current industry, you always run the risk of running into the same people later on. So you're far better off taking the high road and making sure your exit is a classy one.