On the flip side, if you loved your job, your coworkers, your boss, the cappuccino machine, everything about the place, don't write page upon page waxing rhapsodic about all that you're giving up by leaving. A brief, heartfelt compliment to the company, or a thank you, is fine.
Even if you're not close with your boss, chances are you have a working, first_name_basis relationship. Maintaining that in your official letter is okay. You don't need to keep a Victorian level of formality here__just make sure it's a professional tone.