Prepare for It. In this case, all you can do is politely deliver your resignation, then strive to make the transition as easy as possible for your team. Your manager may not have the ideal reaction to your news__and your workplace may not be the most pleasant environment for the next two weeks__but to avoid burning bridges, it's best to work through it with a positive attitude.
A resignation letter can also help your boss and your company start the transition process, get a replacement for you approved, and start planning internally, etc. The paper trail is beneficial all around. So what should go into your letter? Let's look at some examples of what to do (and perhaps more importantly, what not to do).