The Hand_off. Finally, state your willingness to help out with the transition. You don't need to go into great detail (and definitely don't promise anything you can't deliver), but a couple of lines stating that you'll ensure a smooth wrap_up of your duties will show that you're in the game until the very end. Obviously, feel free to adjust this a bit based on your experience and your company culture, then submit it via the typical procedures at your company.
And sure, this could be an email (all of the same principles would apply), but a letter makes things official in every sense. It also gives you a prop to take along to the face_to_face meeting with your boss, when you let him or her know that you're leaving.