Turning in your two weeks notice can be terrifying__because no matter how well you think you know your supervisor, you can never be 100% sure of his or her reaction. Will he be furious and insist on walking you out the door immediately? Will she beg you to stay, enticing you with an enormous raise? Or will he be completely civil and wish you the best of luck?
Acceptance With Displeasure. It's possible that your boss won't take immediate action like the reaction above__but will make it clear that he or she isn't exactly happy about your resignation. Maybe, for example, she'll mutter a curt, "Thank you for letting me know," followed by two weeks of obvious displeasure or denial that you're leaving__through gruff comments ("You know, you're really leaving us in the lurch") or a refusal to interact with you more than absolutely necessary.