On the flip side, if you loved your job, your coworkers, your boss, the cappuccino machine, everything about the place, don't write page upon page waxing rhapsodic about all that you're giving up by leaving. A brief, heartfelt compliment to the company, or a thank you, is fine.
The Hand_off. Finally, state your willingness to help out with the transition. You don't need to go into great detail (and definitely don't promise anything you can't deliver), but a couple of lines stating that you'll ensure a smooth wrap_up of your duties will show that you're in the game until the very end. Obviously, feel free to adjust this a bit based on your experience and your company culture, then submit it via the typical procedures at your company.