Spot the Signs. Do you have a good relationship with your manager? Is he or she relatively reasonable? Do you have regular one_on_ones where you talk about your career goals and growth? If so, it's likely that your boss will accept your resignation with grace, help develop a plan of action for your last two weeks, and maybe even attend your farewell happy hour.
If You Want to Do More Than Just the Basics with Your Resignation Letter. You can always write more, and craft a longer resignation letter, but the truth is that it isn't necessary. You can add a portion of the note where you thank your manager or boss for the opportunities and time you have had together, or add that you hope to keep in touch, but in reality, if you really feel this way you probably should make an effort and find an opportunity to say these things in person (rather than getting an email).