Spot the Signs. Do you have a good relationship with your manager? Is he or she relatively reasonable? Do you have regular one_on_ones where you talk about your career goals and growth? If so, it's likely that your boss will accept your resignation with grace, help develop a plan of action for your last two weeks, and maybe even attend your farewell happy hour.
After that, you're ready to close out your letter and move on. The basic closings are fine here__again, you don't need to go overly sentimental or formal, but you should also write as if it will be read by anyone at the company. And with that signing flourish, you're done! You've resigned, and you're ready for your exciting new job.