If You Want to Do More Than Just the Basics with Your Resignation Letter. You can always write more, and craft a longer resignation letter, but the truth is that it isn't necessary. You can add a portion of the note where you thank your manager or boss for the opportunities and time you have had together, or add that you hope to keep in touch, but in reality, if you really feel this way you probably should make an effort and find an opportunity to say these things in person (rather than getting an email).
A Professional Greeting. Your letter should be addressed to your boss. There's a good chance that this letter will merely end up in a file in HR, but it starts with your boss. Assuming this is someone with whom you work reasonably close with on a daily basis, it doesn't have to be super stiff and formal. Specific and professional is the right tone here.