Spot the Signs. Do you have a good relationship with your manager? Is he or she relatively reasonable? Do you have regular one_on_ones where you talk about your career goals and growth? If so, it's likely that your boss will accept your resignation with grace, help develop a plan of action for your last two weeks, and maybe even attend your farewell happy hour.
Spot the Signs. According to Alison Green, who writes the blog Ask a Manager, this is common practice for some industries, especially if you're leaving to work for a direct competitor. However, in those situations, you'll likely know it's coming and can prepare accordingly.