Why might you still want to write a resignation letter? Many experts believe that writing a formal or even a basic resignation letter when you're leaving your current job helps make you seem more courteous and professional. However, the real reason to write a resignation letter is to create a paper trail documenting that you have given notice (if your employer requires two weeks notice or some other amount of notice) on a certain date, and to formally kick of the process should there be any legal hiccups (quite rare) with incorrectly processing your final paycheck and last day of benefits.
Acceptance With Grace. The best_case scenario__and honestly, the most common reaction__is that your boss will accept your resignation with understanding and sincere congratulations. Your manager will be happy to see that you're advancing your career and moving on to something bigger and better.